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Croscarmellose Sodium (CCS) HiLose TM

HiloseTM, is an internally cross linked polymer of carboxymethyl cellulose sodium which is used as a super disintegrant in pharmaceutical formulations. Cross Linking makes it insoluble & highly absorbent material, resulting in excellent swelling properties. Its unique fibrous nature gives it excellent water wicking capabilities.

Advantages

  • Rapid swelling characteristics
  • Superior flow property
  • Good stability with API
  • Long term stability
  • Fast tablet disintegration
  • Fast drug dissolution
  • Economical

Applications

  • Used in oral pharmaceutical formulations as a super disintegrant for Capsules, Tablets and Granules Formulations.
  • Used in tablets including dietary supplements to assist the tablet in disintegrating in the intestinal track.
  • In tablet formulations, it is used in both direct compression and wet granulation processes.
  • Effective in combination with both insoluble filler-binders and slightly soluble to soluble filler-binder.
  • Used in wet granulations as intra granular or extra granular super disintegrant.