Microcrystalline Cellulose with Lactose Monohydrate - HiCellac 100

HiCellac is a co-processed product of Microcrystalline Cellulose and Lactose Monohydrate, creating a mono particulate system having two compaction mechanisms, brittle fracture and plastic deformation, within individual particles. HiCellac comprises of 25% microcrystalline cellulose and 75% lactose monohydrate.

Advantages

• Excellent flowability
• Improved content uniformity
• Consistent tablet hardness
• Superior compactability
• Lower friability
• Better tablet surface for smooth and economical coating

Applications

• HiCellac 100 is used in direct compression
• In dry granulation and capsule filling
• Suitable for low dose formulations where API content uniformity is critical
• Excellent compaction properties and tablet hardness, making HiCellac 100 suitable for high dose formulations also

Specification

Characteristics	HiCellac 100 Specification
Assay as microcrystalline cellulose	23.0% – 27.0%
Assay as lactose monohydrate	73.0% – 77.0%
Particle size distribution
< 250 micron	Not Less Than 90%
< 160 micron	45% - 70%
< 32 micron	Not More Than 15 %