High Functionality Excipients - HiCel^TM SMCC

The properties of microcrystalline cellulose have been tried to improve by co-processing MCC with colloidal silicon dioxide. HiCel^TM SMCC is silicified microcrystalline cellulose, a combination of 98% microcrystalline cellulose (MCC) and 2% colloidal silicon dioxide (CSD). HiCel^TM SMCC has unique combination which result in optimum compaction and superior flow properties.

Advantages

• Superior flow characteristics
• Dust free handling
• Insoluble in water and inert in nature
• Consistent and stable ingredient
• Excellent compactibility
• Excellent binding characteristics due to higher surface area
• Improved lubrication properties results in excellent blend homogeneity and content uniformity
• Increased production capacity while lowering stress on equipment
• Smaller tablet size with shorter disintegration time

Grades & Applications

Silicified microcrystalline cellulose (SMCC) should have better compaction properties and it is more resistant to wet granulation than conventional MCC grades.

HiCel™ Silicified Microcrystalline Cellulose ​(SMCC) product brochure constitutes of product specifications and  results of below insightful comparative studies :

1. Content Uniformity in MCC/SMCC in small dosage form.
2. Comparison of Tensile strength between physical blend vs co-processed.
3. Comparison of Dissolution between physical blend vs co-processed.
4. Comparison of Content uniformity of API  between physical blend vs co-processed.
5. Comparison of Friability  between physical blend vs co-processed.
6. And many more....

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Direct Compressible Tablet Preparation of Health Supplement L-Cystine 550 mg With HiCel SMCC LM 90-nutraceutical application leaflet constitutes of formulation specifications and below results obtained from the studies:

1. Ingredient composition for the formulation
2. Physical parameter evaluation of L-Cystine and final blend formulated in our lab.
3. Weight Uniformity of L-Cystine Tablet.
4. 4.Hardness Uniformity of L-Cystine Tablet.
5. And many more....

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